Advancing hypo recovery for people living with type 1 diabetes.
Standard glucose corrects the low. It doesn't treat what comes after — the brain fog, fatigue, and repeat episodes that disrupt your patients' lives for hours.
Standard glucose corrects the low. It doesn't treat what comes after — the brain fog, fatigue, and repeat episodes that disrupt your patients' lives for hours.
The unmet need
For many people with type 1 diabetes, hypoglycemia is not an occasional event — it is a repeated disruption to daily life.
Standard glucose-only options reliably correct blood sugar but often fail to deliver full functional recovery. Many suffer rebound highs, recurrent lows, and a lingering hypo "hangover" even after glucose levels have normalized.
The MESH™ approach
Klario® is a novel recovery drink that combines 15g of fast‑acting carbohydrate with adaptive energy sources - beta‑hydroxybutyrate and lactate.
Its proprietary multi-substrate system, MESH™, was designed to support rapid blood glucose correction and sustained brain energy recovery during the post-hypo recovery period.
An independent randomized controlled crossover study in adults with type 1 diabetes, using continuous glucose monitoring (CGM) and patient-reported outcomes in a real-world setting, comparing Klario directly against standard of care glucose gel.
Based on objective CGM data, Klario was associated with improved glycemic stability and reduced recurrence.
Participants reported fewer “hypo hangover” symptoms, faster return to normal activities, and less severe after-effects such as brain fog and fatigue.
Patient perspectives
For your patients
Klario is a functional food available directly from myklario.com. Your patients can order it without a prescription. Here's how to get started.
Usually dispatched within 3–5 working days
Latest publications
Studies show that cognitive function, including thinking, attention and reaction time, can remain impaired for some time after blood glucose has been corrected.
This suggests that restoring glucose in the bloodstream does not immediately restore energy supply within brain cells, potentially due to a hypothesized “brain energy bottleneck.”
Alternative energy sources such as BHB and lactate may help by entering the brain’s energy-producing pathways through routes that do not depend on the same step in glucose metabolism.
Providing these substrates alongside glucose may therefore support energy production while normal glucose use recovers.
This is the scientific rationale behind novel nutritional approaches based on multi-energy substrates for hypoglycemia (MESH).
Video coming soon
The people behind the research
Klario's MESH™ formula and research program have been developed in collaboration with leading clinicians and researchers in diabetes, metabolic medicine, and exercise physiology.
SHIFT PROGRAM
SHIFT (Supporting Hypoglycemia Innovation and Future Treatments) is Klario's free membership program for diabetes care professionals. Join a growing community dedicated to improving patient outcomes in hypo management.
Potential to collaborate on Klario's future research program.
Accredited educational sessions with leading diabetes clinicians and researchers.
Ready-to-use patient leaflets, prescribing guides, and formulary data.
A voice in shaping hypoglycemia management standards and real-world evidence generation.
Receive exclusive discounts and special offers for your clinic and your patients.
Free membership for registered healthcare professionals. Takes 2 minutes to sign up.
We've answered the most common clinical and practical questions on our FAQ page.